smiles_to_molecule() does not generate coordinates. This is an OpenBabel known limitation.
MDL NoStructs are weakly supported but not recommended:
- They will always evaluate to 'false' in matches.
- molecule_to_inchi() cannot handle NoStructs and exits the server with SIGQUIT (for whatever reason...)
- Test for Nostructs with is_nostruct(); Better yet kill 'em all, for you have NULL.
The performance enhancements for completely circular graphs like Buckyballs or Nanotubes might produce false positives but none have been observed yet.
